At a glance
ClinicalIndex Comparison RecordStandardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
A Randomized, Controlled, Open-label, 4-arm Parallel Group Study to Evaluate the Effect of Switching From Cigarette Smoking to the Use of IQOS in Healthy Adult Current Smokers on Exercise Capacity and Trainability
In Brief
A clinical study evaluating IQOS + Exercise Training Program, IQOS without Exercise Training Program, and 2 other interventions for Smoking and Exercise Capacity. Completed, enrolled 94 participants across 1 site.
Detailed Summary
This exploratory study is part of the global clinical assessment program of IQOS. It was designed to provide scientific evidence to further substantiate the reduced risk potential of using a heated tobacco product (the Tobacco Heating System \[THS\] marketed as IQOS) as compared to smoking cigarettes. The main goals of this exploratory study were to assess whether switching from cigarette smoking to using IQOS would influence 1) maximum oxygen uptake during incremental exercise (VO2max) and exercise capacity, 2) ability to perform exercise training and thereby influence 3) VO2max after 12 weeks of exercise training, 4) physiological parameters and biological health markers, and finally 5) physical activity levels in daily life.
Study Details
Timeline
Interventions
Switch to IQOS use + participation in a training program
Switch to IQOS use only, without participation in a training program
Continue to smoke cigarettes + participation in a training program
Switch to smoking abstinence + participation in a training program