CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 400 enrolled
Drug / intervention
rapid whole genomic sequencing (rWGS)other
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03890679
NCT03890679N/ACompleted

Genomic Medicine for Ill Neonates and Infants (The GEMINI Study)

Tufts Medical Center·interventional·Posted Mar 26, 2019·Updated Aug 6, 2025

In Brief

A clinical study evaluating rapid whole genomic sequencing (rWGS) for Pediatric: Genetic Syndrome. Completed, enrolled 400 participants across 6 sites.

Detailed Summary

The Genomic Medicine for Ill Neonates and Infants (The GEMINI Study) is a research study aimed at comparing the clinical and economic utility of performing rapid whole genomic sequencing versus a targeted genomic sequencing panel on neonates and infants suspected of having a genetic disorder. This study is funded by the National Institutes of Health. This multicenter, prospective clinical trial will enroll 400 subjects at the Floating Hospital for Children at Tufts Medical Center (Boston, MA), Cincinnati Children's Hospital Medical Center (Cincinnati, OH), Mount Sinai Kravis Children's Hospital (New York, NY), North Carolina Children's Hospital (Chapel Hill, NC), Children's Hospital of Pittsburgh (Pittsburgh, PA), and Rady Children's Hospital (San Diego, CA).

Study Details

Timeline

N/ACompletedFinished
2020202120222023202420252026
First PostedMar 26, 2019
Enrollment StartMay 24, 2019
Primary CompletionNov 1, 2021
Study CompletionNov 1, 2022
TodayJul 2, 2026
Enrollment to primary: 2.4 yearsPosted 7.3 years ago

Interventions

rapid whole genomic sequencing (rWGS)other

rWGS and NewbornDx are genomic sequencing platforms