CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 50,207 enrolled
Drug / intervention
Interview +2 moreother
Likely dose
Not stated in record
Key inclusion· 1
  • Active diagnosis of solid or liquid cancer
Key exclusion· 1
  • Minors (under age 18) excluded from questionnaires, subject to standard of care for questionnaire assignment

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03892967
NCT03892967N/ACompleted

Enhanced, EHR-Facilitated Cancer Symptom Control (E2C2) Trial

Mayo Clinic·interventional·Posted Mar 27, 2019·Updated Oct 7, 2025

In Brief

A clinical study evaluating Interview, Quality-of-Life Assessment, and 1 other intervention for Hematopoietic and Lymphoid Cell Neoplasm and Malignant Solid Neoplasm. Completed, enrolled 50,207 participants across 1 site.

Detailed Summary

This early phase I trial investigates enhanced, electronic health record (EHR)-facilitated cancer system control. Cancer and its treatment are often associated with severe, disabling symptoms that have been causally linked to diminished survival, increased healthcare utilization, degraded quality of life, unemployment, and non-adherence to recommended cancer treatments. Collaborative case management for control of moderate or worse sleep disturbance, pain, anxiety, depression, fatigue (SPADE symptoms), and physical dysfunction among cancer survivors and patients with cancer may improve quality of life, symptom severity, and adherence to cancer treatment, and may also reduce need for acute care.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States

Timeline

N/ACompletedFinished
2020202120222023202420252026
First PostedMar 27, 2019
Enrollment StartMar 28, 2019
Primary CompletionJan 31, 2023
TodayJul 2, 2026
Enrollment to primary: 3.8 yearsPosted 7.3 years ago

Interventions

Interviewother

Participate in interview

Quality-of-Life Assessmentother

Ancillary studies

Questionnaire Administrationother

Ancillary studies