CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 57 enrolled
Drug / intervention
IFX-1 +3 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03895801
NCT03895801Phase 2Completed

A Randomized, Double-blind, Double-dummy, Active-controlled, Multicenter, 2-part Phase II Study on Replacement of Steroids by IFX-1 in Active Granulomatosis With Polyangiitis (GPA) and Microscopic Polyangiitis (MPA)

InflaRx GmbH·interventional·Posted Mar 29, 2019·Updated Aug 25, 2022

In Brief

A Phase 2 clinical trial evaluating IFX-1, Placebo-IFX-1, and 2 other interventions for Granulomatosis With Polyangiitis (GPA) and Microscopic Polyangiitis (MPA). Completed, enrolled 57 participants across 76 sites in 11 countries.

Detailed Summary

The purpose of the study is to evaluate the efficacy of IFX-1 treatment as replacement for glucocorticoid (GC) therapy in subjects with polyangiitis (GPA) or microscopic polyangiitis (MPA).

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesBelgium, Czechia, France, Germany, Italy, Netherlands, Russia, Spain, Sweden, Switzerland, United Kingdom
Collaborators--

Timeline

Phase 2CompletedFinished
2020202120222023202420252026
First PostedMar 29, 2019
Enrollment StartApr 3, 2019
Primary CompletionApr 14, 2021
Study CompletionJun 8, 2021
TodayJul 2, 2026
Enrollment to primary: 2.0 yearsPosted 7.3 years ago

Interventions

IFX-1drug

intravenously administered

Placebo-IFX-1drug

intravenously administered

Glucocorticoid (GC)drug

orally administered

Placebo-Glucocorticoid (Placebo-GC)drug

orally administered