CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 92 enrolled
Drug / intervention
Dexamethasonedrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03900624
NCT03900624Phase 4Completed
CompareCT.gov

Ideal Steroids for Asthma Treatment in the PICU (iSTAT PICU): A Prospective, Comparative, Single-arm Study Assessing Dexamethasone Versus Methylprednisolone in Severe Status Asthmaticus Admitted to the Pediatric Intensive Care Unit

Johns Hopkins All Children's Hospital·interventional·Posted Apr 3, 2019·Updated Feb 23, 2024

In Brief

A Phase 4 clinical trial evaluating Dexamethasone for Asthma Childhood. Completed, enrolled 92 participants across 1 site.

Detailed Summary

Determine if differences in (1) pediatric intensive care unit length of stay, (2) continuous nebulized albuterol duration, and (3) a composite outcome of advanced asthma therapy incidence including use of non-invasive ventilation (NIV), terbutaline, inhaled helium and mechanical ventilation between cohorts of children admitted with status asthmaticus to the PICU treated with either IV dexamethasone (DM) or methylprednisolone (MP).

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsAsthma Childhood
CountriesUnited States
Collaborators--

Timeline

Phase 4CompletedFinished
2020202120222023202420252026
First PostedApr 3, 2019
Enrollment StartApr 21, 2019
Primary CompletionDec 31, 2021
Study CompletionMay 15, 2022
TodayJul 2, 2026
Enrollment to primary: 2.7 yearsPosted 7.2 years ago

Interventions

Dexamethasonedrug

Non-randomized, open-label, prospective use of intravenous dexamethasone for children admitted to the PICU with status asthmaticus