CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 66 enrolled
Drug / intervention
Ligelizumabbiological
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03907878
NCT03907878Phase 3Completed

A Multi-center, Open-label Study to Investigate the Safety/Tolerability and Efficacy of Ligelizumab (QGE031) in the Treatment of Adult Japanese Patients With Chronic Spontaneous Urticaria (CSU) Inadequately Controlled With H1 Antihistamines

Novartis Pharmaceuticals·interventional·Posted Apr 9, 2019·Updated Mar 6, 2025

In Brief

A Phase 3 clinical trial evaluating Ligelizumab for Chronic Spontaneous Urticaria. Completed, enrolled 66 participants across 11 sites.

Detailed Summary

The purpose of this study was to evaluate the safety and efficacy of ligelizumab in adult Japanese subjects with CSU, who remain symptomatic despite treatment with H1-antihistamines (AHs) at locally approved doses. The study population consisted of 66 male and female subjects aged ≥ 18 years who were diagnosed with CSU and who remained symptomatic despite the use of H1-AH. This was a Phase III multi-center, open-label, single arm study. There was a screening period of up to 28 days, a 52 week treatment period, and a 12 week post-treatment follow-up period.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesJapan
Collaborators--

Timeline

Phase 3CompletedFinished
2020202120222023202420252026
First PostedApr 9, 2019
Enrollment StartApr 13, 2019
Primary CompletionJan 26, 2022
TodayJul 2, 2026
Enrollment to primary: 2.8 yearsPosted 7.2 years ago

Interventions

Ligelizumabbiological

Liquid in vial