CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 139 enrolled
Drug / intervention
mode of mechanical ventilationprocedure
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03909854
NCT03909854N/ACompleted
CompareCT.gov

Pragmatic Investigation of Volume Targeted Ventilation-1 (PIVOT-1)

Wake Forest University Health Sciences·interventional·Posted Apr 10, 2019·Updated Jul 7, 2023

In Brief

A clinical study evaluating mode of mechanical ventilation for Respiratory Failure and 2 related conditions. Completed, enrolled 139 participants across 1 site.

Detailed Summary

This proposal will test the feasibility of implementing an assist volume control ventilation protocol in patients receiving mechanical ventilation in the medical intensive care unit. The trial will consist of a before-and-after trial design of block assignment to either adaptive pressure control (baseline) or assist volume control . This is a feasibility study looking at the management of patients in the ventilator.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsRespiratory Failure, Acute Respiratory Distress Syndrome (ARDS), Ventilator Lung
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
2020202120222023202420252026
First PostedApr 10, 2019
Enrollment StartSep 9, 2019
Primary CompletionNov 12, 2019
Study CompletionFeb 20, 2020
TodayJul 2, 2026
Enrollment to primary: 2 monthsPosted 7.2 years ago

Interventions

mode of mechanical ventilationprocedure

Adaptive Pressure Control mechanical ventilation is a dual controlled mode that is designed to auto-control flow and minimize inspiratory pressure while delivering a provider-determined tidal volume. Assist Volume Control mechanical ventilation is a mode in which the respiratory care provider determines patient tidal volume and flow.