CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 50 enrolled
Drug / intervention
triamcinolone acetonide injection +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03914092
NCT03914092Phase 4Completed

Intralesional Steroid Injection Versus Accent Method of Voice Therapy in Management of Vocal Nodules: A Randomized Controlled Trial

Assiut University·interventional·Posted Apr 16, 2019·Updated Jan 16, 2026

In Brief

A Phase 4 clinical trial evaluating triamcinolone acetonide injection and Smith Accent method of voice therapy for Vocal Nodules in Adults. Completed, enrolled 50 participants across 1 site.

Detailed Summary

Vocal nodules represent 16 % of benign vocal fold lesions.They are caused by chronic voice abuse or misuse and often occur in children and adult females. The resultant dysphonia leads to personal, social and occupational problems. The first line of treatment is voice rest and voice therapy. The Accent method is a holistic technique for behavior readjustment voice therapy which targets various voice parameters as loudness, pitch and timbre. However, voice rest and voice therapy are sometimes difficult to be carried out in patients with voice-related occupations. So, complete resolution may not be possible in all patients. When voice therapy is inefficient, resection is performed by laryngeal microsurgery under general anesthesia. However, the role of surgery is much restricted.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesEgypt
Collaborators--

Timeline

Phase 4CompletedFinished
2020202120222023202420252026
First PostedApr 16, 2019
Enrollment StartJun 29, 2019
Primary CompletionAug 15, 2022
Study CompletionAug 28, 2023
TodayJul 2, 2026
Enrollment to primary: 3.1 yearsPosted 7.2 years ago

Interventions

triamcinolone acetonide injectiondrug

0.1- 0.3 mm percutaneous intralesional injection

Smith Accent method of voice therapybehavioral

regular sessions of smith accent voice therapy (about 24 sessions, twice session / week) for 3 months