CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 90 enrolled
Drug / intervention
Mirtazapine 15 MG Oral Tabletdrug
Likely dose
Mirtazapine 15 MG Oral Tabletfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03921151
NCT03921151Phase 2Completed
CompareCT.gov

5-HT2AR: 5HT2CR Balance in Brain Connectivity in Cocaine Dependence

Virginia Commonwealth University·interventional·Posted Apr 19, 2019·Updated Nov 22, 2021

In Brief

A Phase 2 clinical trial evaluating Mirtazapine 15 MG Oral Tablet for Cocaine Dependence. Completed, enrolled 90 participants across 1 site.

Detailed Summary

This project will evaluate the role of the 5-HT2CR:5-HT2AR balance in impulsive action and cue reactivity in cocaine-dependent subjects as compared to non-drug using controls.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsCocaine Dependence
CountriesUnited States
CollaboratorsThe University of Texas Medical Branch, Galveston, National Institute on Drug Abuse (NIDA)

Timeline

Phase 2CompletedFinished
201520162017201820192020202120222023202420252026
First PostedApr 19, 2019
Enrollment StartMay 13, 2014
Primary CompletionJan 24, 2019
TodayJul 2, 2026
Enrollment to primary: 4.7 yearsPosted 7.2 years ago

Interventions

Mirtazapine 15 MG Oral Tabletdrug

The intervention will be a 15mg of mirtazapine oral tablet given to participants prior to their treatment scan and assessments. In order to ensure that biases or social desirability do not contaminate baseline assessments, all participants will also be given a tablet consisting of dextrose in gelatin prior to their baseline scan and assessment.