CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 274 enrolled
Drug / intervention
Bimekizumab +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03928704
NCT03928704Phase 3Completed

A Phase 3, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study Evaluating the Efficacy and Safety of Bimekizumab in Subjects With Active Nonradiographic Axial Spondyloarthritis

UCB Biopharma SRL·interventional·Posted Apr 26, 2019·Updated Dec 24, 2025

In Brief

A Phase 3 clinical trial evaluating Bimekizumab and Placebo for Nonradiographic Axial Spondyloarthritis. Completed, enrolled 274 participants across 83 sites in 13 countries.

Detailed Summary

The purpose of the study is to demonstrate the efficacy, safety and tolerability of bimekizumab administered subcutaneously (sc) compared to placebo in the treatment of subjects with active nonradiographic axial spondyloarthritis (nr-axSpA).

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesBelgium, Bulgaria, China, Czechia, France, Germany, Hungary, Japan, Poland, Spain, Turkey (Türkiye), United Kingdom, United States
Collaborators--

Timeline

Phase 3CompletedFinished
2020202120222023202420252026
First PostedApr 26, 2019
Enrollment StartApr 25, 2019
Primary CompletionJun 29, 2022
Study CompletionApr 17, 2023
TodayJul 2, 2026
Enrollment to primary: 3.2 yearsPosted 7.2 years ago

Interventions

Bimekizumabdrug

Subjects will receive bimekizumab at pre-specified time-points.

Placeboother

Subjects will receive placebo at pre-specified time-points during the Double-Blind Treatment Period.