At a glance
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Aspirin Resistance in Obstructive Sleep Apnea Patients (ARISA Trial)
In Brief
An observational study evaluating Aspirin Resistance testing for Obstructive Sleep Apnea. Completed, enrolled 63 participants across 1 site.
Detailed Summary
Obstructive Sleep Apnea (OSA) patients are at increased risk of major cardiovascular events, so many patients take aspirin for prevention. Poor responsiveness to aspirin is a major clinical concern because it can potentially worsen the prognosis of OSA patients. However, continuous positive airway pressure (CPAP) therapy that is considered standard of care for OSA treatment may potentially lead to improvement in responsiveness to aspirin. This study will determine whether CPAP therapy decreases patients' aspirin resistance in OSA patients with a new diagnosis or existing moderate to severe OSA who are treated with CPAP and take aspirin for prevention.
Study Details
Timeline
Interventions
Aspirin resistance will be measured using platelet aggregometry (VerifyNow assay)