CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 515 enrolled
Drug / intervention
MD-7246 +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03931785
NCT03931785Phase 2Completed

A Phase 2, Randomized, Double-blind, Placebo-controlled, Parallel-group, Dose-range-finding Study of MD-7246 Administered Orally for 12 Weeks to Treat Abdominal Pain in Patients With Diarrhea-predominant Irritable Bowel Syndrome

Ironwood Pharmaceuticals, Inc.·interventional·Posted Apr 30, 2019·Updated Mar 12, 2021

In Brief

A Phase 2 clinical trial evaluating MD-7246 and Placebo for Irritable Bowel Syndrome With Diarrhea (IBS-D). Completed, enrolled 515 participants across 80 sites.

Detailed Summary

To evaluate the safety and tolerability, treatment effect on abdominal pain, and dose response of MD-7246 administered orally to patients with diarrhea-predominant irritable bowel syndrome (IBS-D).

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
CollaboratorsAllergan Sales, LLC

Timeline

Phase 2CompletedFinished
2020202120222023202420252026
First PostedApr 30, 2019
Enrollment StartMay 1, 2019
Primary CompletionFeb 26, 2020
Study CompletionMar 11, 2020
TodayJul 2, 2026
Enrollment to primary: 10 monthsPosted 7.2 years ago

Interventions

MD-7246drug

Oral tablet

Placebodrug

Matching oral tablet