CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 47 enrolled
Drug / intervention
Latanoprost 0.005% +3 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03949244
NCT03949244Phase 4Completed
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Effect of Nailfold Application of Latanoprostene Bunod on Nailfold Capillary Blood Flow

Icahn School of Medicine at Mount Sinai·interventional·Posted May 14, 2019·Updated Sep 29, 2021

In Brief

A Phase 4 clinical trial evaluating Latanoprost 0.005%, Latanoprost bunod 0.024%, and 2 other interventions for Glaucoma, Open-Angle. Completed, enrolled 47 participants across 1 site.

Detailed Summary

The purpose of this study is to look at the relationship of small blood vessels irregularities observed with an imaging system called video nailfold capillaroscopy in people with primary open-angle glaucoma. Nailfold capillaroscopy (NFC) is a video camera with a magnifying lens used for studying the movement of blood in small blood vessels. It is simple, safe and does not penetrate the skin. The skin fold that is at the tip of the finger is called the "nailfold". NFC has been used to assess blood vessel narrowing in patients with glaucoma.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsGlaucoma, Open-Angle
CountriesUnited States
Collaborators--

Timeline

Phase 4CompletedFinished
2020202120222023202420252026
First PostedMay 14, 2019
Enrollment StartAug 15, 2019
Primary CompletionOct 1, 2020
TodayJul 2, 2026
Enrollment to primary: 1.1 yearsPosted 7.1 years ago

Interventions

Latanoprost 0.005%drug

Latanoprost 0.005% will be applied to the nailfold and images of the blood flow in the nailfold capillaries will be acquired.

Latanoprost bunod 0.024%drug

Latanoprost bunod 0.024% will be applied to the nailfold and images of the blood flow in the nailfold capillaries will be acquired.

Normal saline 0.9%drug

Normal saline 0.9% will be applied to the nailfold and images of the blood flow in the nailfold capillaries will be acquired.

Nailfold capillaroscopyother

An imaging system and does not penetrate the skin. A video camera with a magnifying lens used for studying the movement of blood in small blood vessels at the nailfold of the 4th finger.