CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 49 enrolled
Drug / intervention
Mindfulness Intervention +1 morebehavioral
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03949296
NCT03949296N/ACompleted

A Randomized, Placebo-Controlled Study of Mindfulness Meditation in Treating Insomnia in Multiple Sclerosis

Griffin Hospital·interventional·Posted May 14, 2019·Updated Feb 26, 2020

In Brief

A clinical study evaluating Mindfulness Intervention and Sleep Hygiene for Insomnia Chronic and Multiple Sclerosis. Completed, enrolled 49 participants across 1 site.

Detailed Summary

Purpose To determine whether Mindfulness-Based Treatment for Insomnia (MBTI) is more effective in the treatment of chronic insomnia disorder (CID) in patients with multiple sclerosis (MS) when compared with standard sleep hygiene counseling. Specific Aims / Hypotheses Our specific aims are to determine: * Whether MBTI is more effective than standard sleep hygiene counseling in improving objectively-measured sleep quality among this group of MS patients with CID, as measured by the Fitbit Charge 2 activity tracker. * Whether MBTI is more effective than standard sleep hygiene counseling in improving self-reported sleep quality among this group of MS patients with CID, as measured by the Pittsburgh Sleep Quality Index (PSQI). * Whether MTBI is more effective than standard sleep hygiene counseling in reducing self-reported severity of insomnia among this group of MS patients with CID, as measured by the Insomnia Severity Index (ISI). * Whether MBTI is more effective than standard sleep hygiene counseling in improving self-reported quality of life among this group of MS patients with CID, as measured by the Multiple Sclerosis Quality of Life Inventory (MSQLI). We hypothesize that among study participants with MS and CID: * MBTI will improve their objectively-measured sleep quality, as measured by the Fitbit Charge 2 activity tracker. * MBTI will improve their self-reported sleep quality, as measured by the PSQI. * MBTI will reduce their self-reported severity of insomnia, as measured by the ISI. * Improvement in sleep quality and reduction in insomnia severity will result in improvement in self-reported quality of life, as measured by MSQLI scores. * MBTI will be superior to sleep hygiene counseling in improving sleep quality, reducing insomnia severity, and improving quality of life.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States

Timeline

N/ACompletedFinished
201820192020202120222023202420252026
First PostedMay 14, 2019
Enrollment StartDec 11, 2017
Primary CompletionDec 16, 2019
TodayJul 2, 2026
Enrollment to primary: 2.0 yearsPosted 7.1 years ago

Interventions

Mindfulness Interventionbehavioral

10-session program 1. Introduction to mindfulness and its potential benefits 2. Introduction to mindful practices and yoga poses 3. Conditioned reactions to stress; integrating mindfulness into everyday life 4. Challenges and insights gained in practicing mindfulness 5. Using mindfulness to observe and reduce negative means of reacting to stress, and find more effective responses 6. Reacting vs. responding to stressors 7. Self-regulation and coping with stressors and communication challenges 8. Fostering continuity of moment-to-moment awareness while practicing different forms of mindfulness 9. Choosing and creating one's own blend of mindfulness practices 10. Maintaining momentum to practice mindfulness once the program ends

Sleep Hygienebehavioral

Session includes a handout with15 sleep hygiene tips: 1. Maintain a regular sleep pattern 2. Only try to sleep when feeling tired or sleepy 3. If unable to sleep, do something calm until feeling tired and returning to bed 4. Avoid caffeine \& nicotine for 4-6 hours before going to bed 5. Avoid alcohol for 4-6 hours before going to bed 6. Use the bed only for sleeping and sex 7. Avoid naps during the day 8. Develop rituals to get relaxed and ready to sleep 9. Try a hot bath prior to bedtime 10. Avoid checking the clock during the night 11. Use a sleep diary for a few weeks to track progress 12. Avoid strenuous exercise before bedtime 13. Avoid a heavy meal before bedtime 14. Create a sleep environment that is quiet, comfortable, and dark 15. Maintain a regular daytime routine