CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 45 enrolled
Drug / intervention
Cognitive behavior therapy with social cognitive training (CBT+SCT) +1 morebehavioral
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

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Search/NCT03954392
NCT03954392N/ACompleted

Social Cognitive Training to Enhance the Efficacy of CBT for Depression in Youth: A Developmental Approach

Vanderbilt University·interventional·Posted May 17, 2019·Updated Mar 28, 2023

In Brief

A clinical study evaluating Cognitive behavior therapy with social cognitive training (CBT+SCT) and CBT-only for Depression. Completed, enrolled 45 participants across 2 sites.

Detailed Summary

Depression in youth is a serious public health concern for which more personalized treatments are needed. This study will test the effect of an intervention aimed at enhancing depressed children's social cognitive capacities (e.g., ability to take another's perspective), thereby making treatment of depression in youth more efficient and effective. Participants in both the R61 (N=42) and R33 (N=82) will be youth between 12 and 17 years old currently experiencing a depressive disorder. Youth will be randomized to either an enhanced CBT intervention that teaches social cognitive skills, particularly social perspective taking and theory of mind as compared to CBT only. The primary target is improvement in the social cognitive skills at post treatment in the first trial (R61) and improvements in both social cognitive skills and depressive symptoms at post-treatment and at a 4-month follow-up (R33).

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsDepression
CountriesUnited States

Timeline

N/ACompletedFinished
20192020202120222023202420252026
First PostedMay 17, 2019
Enrollment StartFeb 11, 2019
Primary CompletionAug 31, 2021
Study CompletionSep 30, 2021
TodayJul 2, 2026
Enrollment to primary: 2.6 yearsPosted 7.1 years ago

Interventions

Cognitive behavior therapy with social cognitive training (CBT+SCT)behavioral

The cognitive behavioral therapy is based on Beck's cognitive therapy model for the treatment of depression. We will conduct individual therapy based on the Coping with Stress manual used in other depression treatment studies with adolescents. In addition, the investigators will teach the teen explicitly about theory of mind and social perspective taking during each session and we will use examples from their own life to help them learn the skills.

CBT-onlybehavioral

The cognitive behavioral therapy is based on Beck's cognitive therapy model for the treatment of depression. The investigators will conduct individual therapy based on the Coping with Stress manual used in other depression treatment studies with adolescents.