CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 100 enrolled
Drug / intervention
Trilogy Lithotrite +1 moredevice
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03959683
NCT03959683N/ACompleted

A Prospective Randomized Multicenter Trial Comparing Performance of Two Intracorporeal Lithotripters for Removal of Large Renal Calculi

Indiana University·interventional·Posted May 22, 2019·Updated Apr 12, 2023

In Brief

A clinical study evaluating Trilogy Lithotrite and The ShockPulse-SE Lithotripsy System for Kidney Calculi. Completed, enrolled 100 participants across 4 sites in 2 countries.

Detailed Summary

The purpose of this study is to measure how well two different devices work to break up and remove kidney stones. We are comparing a newer device to an older one to see which one is faster at breaking up kidney stones. We hypothesize that the Trilogy will increase the stone clearance rate by 25% compared to the Shockpulse-SE

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsKidney Calculi
CountriesCanada, United States

Timeline

N/ACompletedFinished
20192020202120222023202420252026
First PostedMay 22, 2019
Enrollment StartFeb 19, 2019
Primary CompletionJul 29, 2020
Study CompletionNov 18, 2020
TodayJul 2, 2026
Enrollment to primary: 1.4 yearsPosted 7.1 years ago

Interventions

Trilogy Lithotritedevice

The Trilogy has been FDA cleared for fragmentation of urinary tract calculi in the kidney, ureter, and bladder. Trilogy is a combined piezoelectric/pneumatic device capable of fragmenting calculi and aspirating stone debris. The novel technology in Trilogy has been demonstrated in bench testing to more quickly disintegrate stones compared to other devices.

The ShockPulse-SE Lithotripsy Systemdevice

The ShockPulse-SE System is an electromechanical device capable of fragmenting calculi and aspirating stone debris. The novel technology in the ShockPulse-SE Lithotripsy System uses a single transducer and proprietary ShockPulse technology to generate both low-frequency mechanical impacts and high-frequency ultrasonic energy which quickly disintegrates stones.