CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 178 enrolled
Drug / intervention
trauma-focused treatmentbehavioral
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03962504
NCT03962504N/ACompleted

An Efficient, Exposure-based Treatment for PTSD Compared to Prolonged Exposure: A Non-inferiority Randomized Trial

VA Office of Research and Development·interventional·Posted May 24, 2019·Updated Jul 18, 2024

In Brief

A clinical study evaluating trauma-focused treatment for PTSD. Completed, enrolled 178 participants across 3 sites.

Detailed Summary

The goal of this study is to examine whether a brief, exposure-based treatment (Written Exposure Therapy) approach is just as effective in the treatment of posttraumatic stress disorder (PTSD) compared with a more commonly used time-intensive approach called Prolonged Exposure. One hundred and fifty Veterans diagnosed with PTSD will be randomly assigned to either Written Exposure therapy or Prolonged Exposure. Veteran participants will be assessed at pre-treatment, and 10-, 20-, and 30- weeks post first treatment session. Primary outcome measure will be PTSD symptom severity. The secondary outcome measure will be quality of life. In addition, treatment dropout during the first five sessions will be examined. WET is expected to have a lower treatment dropout rate relative to PE.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsPTSD
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
2020202120222023202420252026
First PostedMay 24, 2019
Enrollment StartSep 9, 2019
Primary CompletionJan 2, 2023
Study CompletionDec 30, 2023
TodayJul 2, 2026
Enrollment to primary: 3.3 yearsPosted 7.1 years ago

Interventions

trauma-focused treatmentbehavioral

cognitive behavioral treatment for posttraumatic stress disorder that consists of exposure to the trauma memory.