CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 4,124 enrolled
Drug / intervention
Ivermectin +1 moredrug
Likely dose
Ivermectin 6 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03967054
NCT03967054Phase 3Completed
CompareCT.gov

Repeat Ivermectin Mass Drug Administrations for MALaria Control II (RIMDAMAL II): a Double-blind, Cluster-randomized Control Trial for Integrated Control of Malaria

Brian Foy·interventional·Posted May 30, 2019·Updated Apr 10, 2025

In Brief

A Phase 3 clinical trial evaluating Ivermectin and Placebo oral tablet for Malaria. Completed, enrolled 4,124 participants across 1 site.

Detailed Summary

RIMDAMAL II is a double-blind, cluster randomized trial in Burkina Faso designed to test whether repeated ivermectin mass drug administrations, integrated into a monthly delivery platform with standard malaria control measures of seasonal malaria chemoprevention and insecticide-treated bed net distribution in the Sahel, will reduce childhood malaria incidence.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsMalaria
CountriesBurkina Faso
CollaboratorsYale University, Institut de Recherche en Sciences de la Sante-Direction Regionale de l'Ouest, Radboud University Medical Center, PATH, National Institute of Allergy and Infectious Diseases (NIAID)

Timeline

Phase 3CompletedFinished
2020202120222023202420252026
First PostedMay 30, 2019
Enrollment StartJul 13, 2019
Primary CompletionNov 8, 2020
Study CompletionAug 1, 2024
TodayJul 2, 2026
Enrollment to primary: 1.3 yearsPosted 7.1 years ago

Interventions

Ivermectindrug

Ivermectin (6 mg tablet) given monthly from July-October each rainy season as a 3-day course of approximately 300 mcg/kg/day as estimated by height bands.

Placebo oral tabletdrug

placebo in the same size, color and shape at the ivermectin tablet