CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 200 enrolled
Drug / intervention
Rozanolixizumab +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03971422
NCT03971422Phase 3Completed

A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study Evaluating Efficacy and Safety of Rozanolixizumab in Adult Patients With Generalized Myasthenia Gravis

UCB Biopharma SRL·interventional·Posted Jun 3, 2019·Updated Dec 24, 2025

In Brief

A Phase 3 clinical trial evaluating Rozanolixizumab and Placebo for Generalized Myasthenia Gravis. Completed, enrolled 200 participants across 112 sites in 17 countries.

Detailed Summary

The purpose of the MycarinGstudy is to demonstrate the clinical efficacy and to assess safety and tolerability of rozanolixizumab in patients with generalized myasthenia gravis (MG).

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesBelgium, Canada, Czechia, Denmark, France, Georgia, Germany, Hungary, Italy, Japan, Poland, Russia, Serbia, Spain, Taiwan, United Kingdom, United States
Collaborators--

Timeline

Phase 3CompletedFinished
2020202120222023202420252026
First PostedJun 3, 2019
Enrollment StartJun 3, 2019
Primary CompletionAug 31, 2021
Study CompletionOct 26, 2021
TodayJul 2, 2026
Enrollment to primary: 2.2 yearsPosted 7.1 years ago

Interventions

Rozanolixizumabdrug

Rozanolixizumab will be administered by subcutaneous infusion in dosage regimen 1 or 2.

Placeboother

Subjects will receive placebo at pre-specified time points.