CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 48 enrolled
Drug / intervention
Exposure, Relaxation, and Rescripting Therapy +1 morebehavioral
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03974503
NCT03974503N/ACompleted

Characterization of Sleep With Trauma Nightmares Using Ambulatory Sleep Measurement

VA Office of Research and Development·interventional·Posted Jun 5, 2019·Updated Apr 9, 2026

In Brief

A clinical study evaluating Exposure, Relaxation, and Rescripting Therapy and Sleep and Nightmare Management for Nightmares and 4 related conditions. Completed, enrolled 48 participants across 1 site.

Detailed Summary

Trauma-related nightmares in Veterans are associated with poor clinical outcomes, greater substance use, and increased risk of suicide. In spite of an urgent need to reduce the burden of trauma-related nightmares, the underlying physiological changes associated with them are poorly understood, and there are no clear evidence-based recommendations for their treatment. Limitations of current assessment procedures represent a barrier to improved care. In-laboratory sleep studies rarely capture nightmares, limiting the knowledge about them and their response to treatment. This study addresses these limitations by using extended, in-home sleep monitoring to capture sleep data associated with nightmare reports in Veterans, and assessing how these features are altered throughout a cognitive-behavioral nightmare treatment. Results from this study will increase understanding of trauma-related nightmares, and advance strategies for personalizing symptom management for Veterans.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
2020202120222023202420252026
First PostedJun 5, 2019
Enrollment StartDec 2, 2019
Primary CompletionMar 31, 2025
Study CompletionApr 7, 2025
TodayJul 2, 2026
Enrollment to primary: 5.3 yearsPosted 7.1 years ago

Interventions

Exposure, Relaxation, and Rescripting Therapybehavioral

ERRT is a weekly 5-session treatment aimed at reducing chronic trauma nightmares and sleep disturbances in trauma-exposed adults.

Sleep and Nightmare Managementbehavioral

This is a manualized protocol developed to be of similar length but exclude the active components of standard ERRT.