CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 44 enrolled
Drug / intervention
Meditation Intervention A +1 morebehavioral
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03975595
NCT03975595N/ACompleted

Meditation Effects on Brain Function in Rheumatoid Arthritis

Johns Hopkins University·interventional·Posted Jun 5, 2019·Updated Mar 9, 2023

In Brief

A clinical study evaluating Meditation Intervention A and Meditation Intervention B for Rheumatoid Arthritis. Completed, enrolled 44 participants across 1 site.

Detailed Summary

The purpose of this study is to determine the neural mechanisms supporting meditation-based pain relief in rheumatoid arthritis (RA) patients. The scientific premise is that RA patients' use of different meditation practices during noxious thermal stimulation will alter neural function in brain areas associated with pain, evaluation, and emotional appraisal. The investigators will randomize RA patients to a brief 4-session course of Intervention A (n=20) or Intervention B (n=20). At post-intervention, participants will undergo functional MRI (fMRI) using a perfusion-based arterial spin labeling (ASL) technique during noxious thermal stimulation to determine if the meditation practices differentially alter neural function during noxious thermal stimulation.

Study Details

Timeline

N/ACompletedFinished
2020202120222023202420252026
First PostedJun 5, 2019
Enrollment StartOct 7, 2019
Primary CompletionOct 31, 2021
TodayJul 2, 2026
Enrollment to primary: 2.1 yearsPosted 7.1 years ago

Interventions

Meditation Intervention Abehavioral

This will be a brief meditation intervention involving guided breathing and/or attention exercises. Further information is withheld to preserve blinding.

Meditation Intervention Bbehavioral

This will be a brief meditation intervention involving guided breathing and/or attention exercises. Further information is withheld to preserve blinding.