CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 192 enrolled
Drug / intervention
Ropivacaine +3 moredrug
Likely dose
Ropivacaine 60 mlfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03977454
NCT03977454Phase 2Completed

Periarticular Injection Versus Peripheral Nerve Block in Total Hip Arthroplasty: a Single Center Randomized Controlled Trail (RCT) Study

Yale University·interventional·Posted Jun 6, 2019·Updated Sep 23, 2022

In Brief

A Phase 2 clinical trial evaluating Nerve Block, Periarticular Injection (PAI), and 2 other interventions for Hip Arthropathy. Completed, enrolled 192 participants across 1 site.

Detailed Summary

This study will assess if preoperative quadratus lumborum block (QLB)/lateral femoral cutaneous nerve block (LFCNB) with ropivacaine and glucocorticoids provide more effective analgesia than periarticular injection (PAI) with the same mixture in total hip arthroplasty (THA).

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsHip Arthropathy
CountriesUnited States
Collaborators--

Timeline

Phase 2CompletedFinished
2020202120222023202420252026
First PostedJun 6, 2019
Enrollment StartNov 11, 2019
Primary CompletionJun 19, 2021
TodayJul 2, 2026
Enrollment to primary: 1.6 yearsPosted 7.1 years ago

Interventions

Nerve Blockprocedure

Nerve blocks (QLB/LFCNB) to be placed preoperatively with DEX/MPA, per standard of care of anesthesia block service. 1. QLB: 40ml 0.2% ropivacaine with 5 mg DEX/ 40 mg MPA 2. LFCNB: 20ml 0.2% ropivacaine with 5 mg DEX/ 40 mg MPA

Periarticular Injection (PAI)procedure

Intraoperatively, the surgeon will perform PAI per standard of care with the medications: 1\. 60 ml 0.2% ropivacaine and 10 mg DEX/ 80 mg MPA

Ropivacainedrug

60 ml 0.2% ropivacaine

Dexdrug

10 mg DEX/ 80 mg MPA