CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 300 enrolled
Drug / intervention
Freeze Dried Watercress Preparation +1 moredietary
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03978117
NCT03978117Phase 2Completed
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Clinical Trial of Two Study Drinks in Detoxification of Environmental Toxicants and Carcinogens

Masonic Cancer Center, University of Minnesota·interventional·Posted Jun 6, 2019·Updated Nov 21, 2025

In Brief

A Phase 2 clinical trial evaluating Freeze Dried Watercress Preparation and Placebo Preparation for Healthy. Completed, enrolled 300 participants across 1 site.

Detailed Summary

The goal of this research is to determine if consuming one of two study drinks will help enhance the detoxification of multiple environmental toxicants and cancer causing agents, particularly in subjects who are null for glutathione-S-transferase M1 (GSTM1), glutathione-S-transferase T1 (GSTT1), or both. If our research supports this idea, this drink could be an inexpensive dietary component, which could promote good health.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsHealthy
CountriesUnited States
CollaboratorsNational Cancer Institute (NCI)

Timeline

Phase 2CompletedFinished
2020202120222023202420252026
First PostedJun 6, 2019
Enrollment StartFeb 18, 2021
Primary CompletionDec 19, 2023
Study CompletionNov 13, 2024
TodayJul 2, 2026
Enrollment to primary: 2.8 yearsPosted 7.1 years ago

Interventions

Freeze Dried Watercress Preparationdietary

Freeze dried watercress containing gluconasturtiin, which when added to provided water with flavor powder, will result in a total target dose of up to 40 mg/day of 2-phenethyl isothiocyanate (PEITC). Preparation consumed at breakfast, lunch and dinner 3x daily for 2 weeks.

Placebo Preparationdietary

Maltodextrin added to provided water with flavor powder. Preparation consumed at breakfast, lunch and dinner 3x daily for 2 weeks.