CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 12 enrolled
Drug / intervention
Metformin and Spironolactonedrug
Likely dose
Metformin and Spironolactone 500 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03981861
NCT03981861Phase 3Completed
CompareCT.gov

Metabolic and Neuro-Endocrine Effect of Treating PCOS in Adolescents

Children's Mercy Hospital Kansas City·interventional·Posted Jun 11, 2019·Updated Feb 23, 2021

In Brief

A Phase 3 clinical trial evaluating Metformin and Spironolactone for PCOS. Completed, enrolled 12 participants across 1 site.

Detailed Summary

To exam in the effect of a combination of low dose Metformin and Spironolactone on functional brain MRI, menstrual regulation and metabolism in adolescents with PCOS.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsPCOS
CountriesUnited States
Collaborators--

Timeline

Phase 3CompletedFinished
2017201820192020202120222023202420252026
First PostedJun 11, 2019
Enrollment StartJul 2, 2016
Primary CompletionJul 9, 2018
Study CompletionJun 5, 2019
TodayJul 2, 2026
Enrollment to primary: 2.0 yearsPosted 7.1 years ago

Interventions

Metformin and Spironolactonedrug

Oral Metformin tablet (500 mg/tablet) twice daily for 6 months. Oral Spironolactone tablet (50 mg/tablet) once daily for 6 months.