CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 410 enrolled
Drug / intervention
Botulinum Toxin A +2 moredrug
Likely dose
Botulinum Toxin A 20 Unitsfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03985982
NCT03985982Phase 3Completed

Randomized Double Blind Phase 3 Study to Assess the Efficacy and Safety of BoNT/A-DP in the Treatment of Glabellar Lines in Comparison With Placebo Followed by an Open Label Extension Study

Croma-Pharma GmbH·interventional·Posted Jun 14, 2019·Updated Jun 5, 2025

In Brief

A Phase 3 clinical trial evaluating Botulinum Toxin A and Placebo for Glabellar Frown Lines. Completed, enrolled 410 participants across 1 site.

Detailed Summary

The aim of this study is to assess the efficacy and safety of BoNT/A-DP in the treatment of glabellar lines in comparison with placebo, including efficacy after repeat treatments and long term safety.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

Phase 3CompletedFinished
2020202120222023202420252026
First PostedJun 14, 2019
Enrollment StartApr 29, 2019
Primary CompletionDec 4, 2019
Study CompletionDec 22, 2020
TodayJul 2, 2026
Enrollment to primary: 7 monthsPosted 7.0 years ago

Interventions

Botulinum Toxin Adrug

Injection, 20 Units divided in five 0.1 mL i.m injections into the glabellar area

Placebodrug

injection, sodium chloride 0.9 % divided in five 0.1 mL i.m injections into the glabellar area

Botulinum Toxin Adrug

Injection, 20 Units divided in five 0.1 mL i.m injections into the glabellar area in up to 3 treatment cycles