CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 15 enrolled
Drug / intervention
CBT MobileWork-V plus CBT +1 morebehavioral
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04002063
NCT04002063N/ACompleted

Does Adding a Tailored Cognitive Behavioral Therapy (CBT) Mobile Skills App Mediate Higher Rates of Depression Recovery, Adjustment, and Quality of Life in OEF/OIF Veterans Compared to Standard CBT?

VA Office of Research and Development·interventional·Posted Jun 28, 2019·Updated Oct 27, 2025

In Brief

A clinical study evaluating CBT MobileWork-V plus CBT and CBT alone for Depression. Completed, enrolled 15 participants across 9 sites.

Detailed Summary

Depression is a common psychological disorder seen in 18.5% of Operation Enduring Freedom (OEF), Operation Iraqi Freedom (OIF), and Operation New Dawn (OND) Veterans. Improving the rate of depression recovery and remission is vital to enhance OEF/OIF/OND Veteran's ability to improve work and home adjustment and overall quality of life. OEF/OIF/OND Veterans have reported many barriers to following through with Cognitive therapy skills practice assignments, a key component of CBT therapy, the leading therapy for depression in the VA. Smartphone apps have been identified as a useful widely-used tool to improve the effectiveness of psychological treatments. The investigators propose a full-scale multi-site randomized clinical trial (RCT) to measure the efficacy of CBT-D enhanced with CBT MobileWork-V, a comprehensive CBT skill training smartphone app (the experimental arm) for improving CBT understanding and skill acquisition and depressive symptoms, in OEF/OIF Veterans with depression compared to standard CBT-D.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsDepression
CountriesUnited States

Timeline

N/ACompletedFinished
2020202120222023202420252026
First PostedJun 28, 2019
Enrollment StartOct 10, 2022
Primary CompletionMar 31, 2024
TodayJul 2, 2026
Enrollment to primary: 1.5 yearsPosted 7.0 years ago

Interventions

CBT MobileWork-V plus CBTbehavioral

a smartphone app to assist with CBT homework skills practice plus CBT

CBT alonebehavioral

CBT therapy individual