CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 113 enrolled
Drug / intervention
Tislelizumabdrug
Likely dose
Tislelizumab 200mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04004221
NCT04004221Phase 2Completed

A Single-Arm, Multicenter Phase 2 Study of BGB-A317 in Patients With Previously Treated PD-L1+ Locally Advanced or Metastatic Urothelial Bladder Cancer

BeiGene·interventional·Posted Jul 1, 2019·Updated Oct 26, 2024

In Brief

A Phase 2 clinical trial evaluating Tislelizumab for Locally Advanced or Metastatic Urothelial Bladder Cancer. Completed, enrolled 113 participants across 27 sites in 2 countries.

Detailed Summary

This was a single-arm, multicenter, Phase 2 study to evaluate the efficacy and safety of the anti- programmed cell death-1(PD-1) monoclonal antibody BGB-A317 in participants with PD-L1+, locally advanced or metastatic Urothelial Bladder Cancer (UBC) who have progressed during or following a platinum-containing regimen

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesChina, South Korea
Collaborators--

Timeline

Phase 2CompletedFinished
201820192020202120222023202420252026
First PostedJul 1, 2019
Enrollment StartJun 16, 2017
Primary CompletionSep 16, 2019
Study CompletionMar 11, 2021
TodayJul 2, 2026
Enrollment to primary: 2.3 yearsPosted 7.0 years ago

Interventions

Tislelizumabdrug

200mg intravenously (IV) every 3 weeks (Q3W)