CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 80 enrolled
Drug / intervention
Alternate day fasting +1 moreother
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04004403
NCT04004403N/ACompleted
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Alternate Day Fasting Combined With Exercise for the Treatment of Non-alcoholic Fatty Liver Disease (NAFLD)

University of Illinois at Chicago·interventional·Posted Jul 2, 2019·Updated Sep 25, 2025

In Brief

A clinical study evaluating Alternate day fasting and Exercise for Non-Alcoholic Fatty Liver Disease and Obesity. Completed, enrolled 80 participants across 1 site.

Detailed Summary

Approximately 65% of obese individuals have non-alcoholic fatty liver disease (NAFLD), and this condition is strongly related to the development of insulin resistance and diabetes. Innovative lifestyle strategies to treat NAFLD are critically needed. The proposed research will demonstrate that alternate day fasting (ADF) combined with exercise is an effective non-pharmacological therapy to treat NAFLD.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsNon-Alcoholic Fatty Liver Disease, Obesity
CountriesUnited States
CollaboratorsNational Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Timeline

N/ACompletedFinished
2020202120222023202420252026
First PostedJul 2, 2019
Enrollment StartSep 1, 2019
Primary CompletionMay 1, 2024
TodayJul 2, 2026
Enrollment to primary: 4.7 yearsPosted 7 years ago

Interventions

Alternate day fastingother

The diet involves consuming 600 kcal on the "fast day" and eat ad libitum at home on alternating "feed days".

Exerciseother

The exercise intervention involves supervised aerobic exercise program 5 times per week, 40-60 min per session, 60-85% HRmax.