CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 47 enrolled
Drug / intervention
Elobixibat +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04006145
NCT04006145Phase 2Completed

A Double-Blind, Randomized, Placebo-Controlled, Phase 2 Study to Explore the Efficacy and Safety of Elobixibat in Adults With Nonalcoholic Fatty Liver Disease (NAFLD) or Nonalcoholic Steatohepatitis (NASH)

Albireo·interventional·Posted Jul 5, 2019·Updated Feb 5, 2026

In Brief

A Phase 2 clinical trial evaluating Elobixibat and Placebo oral tablet for NAFLD and NASH. Completed, enrolled 47 participants across 10 sites.

Detailed Summary

Double-blind, randomized, placebo-controlled study to explore the efficacy and safety of elobixibat compared to placebo in adults with NAFLD (nonalcoholic fatty liver disease) or NASH (nonalcoholic steatohepatitis)

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsNAFLD, NASH
CountriesUnited States
Collaborators--

Timeline

Phase 2CompletedFinished
2020202120222023202420252026
First PostedJul 5, 2019
Enrollment StartJun 6, 2019
Primary CompletionJun 26, 2020
Study CompletionJul 15, 2020
TodayJul 2, 2026
Enrollment to primary: 1.1 yearsPosted 7.0 years ago

Interventions

Elobixibatdrug

Elobixibat is a small molecule and a potent inhibitor of the ileal bile acid transporter (iBAT).

Placebo oral tabletdrug

Placebo identical in appearance to active drug