CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 61 enrolled
Drug / intervention
Moderate Intensity Aerobic Exercisebehavioral
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04009629
NCT04009629N/ACompleted
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Dementia Risk and Dynamic Response to Exercise

University of Kansas Medical Center·interventional·Posted Jul 5, 2019·Updated May 3, 2022

In Brief

A clinical study evaluating Moderate Intensity Aerobic Exercise for Alzheimer Disease 2 Due to Apoe4 Isoform and Healthy Aging. Completed, enrolled 61 participants across 1 site.

Detailed Summary

Research suggests that physical exercise supports brain health and cognition as we age. The goal of this project is to examine the specific changes in brain blood flow and biological factors in the blood immediately after exercise in older adults who have the APOE4 gene, a genetic risk factor for developing Alzheimer's. Results from this study will help researchers and clinicians understand and measure changes in the body and brain as a function of exercise, and how those changes relate to Alzheimer's risk.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsAlzheimer Disease 2 Due to Apoe4 Isoform, Healthy Aging
CountriesUnited States
CollaboratorsNational Institute on Aging (NIA)

Timeline

N/ACompletedFinished
2020202120222023202420252026
First PostedJul 5, 2019
Enrollment StartOct 25, 2019
Primary CompletionOct 28, 2021
TodayJul 2, 2026
Enrollment to primary: 2.0 yearsPosted 7.0 years ago

Interventions

Moderate Intensity Aerobic Exercisebehavioral

Participants will exercise for 15 minutes in a moderate age-predicted heart rate range. The study team will employ an exercise device such as a treadmill, cycle, or recumbent stepper to maintain control over workload.