CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 40 enrolled
Drug / intervention
Oral-agents/Enemaother
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04013841
NCT04013841N/ACompleted

Bowel Preparation for Left Side Colon Surgery Impact on the Intestinal Microbiome: Oral Preparation vs Enema

Vilnius University·interventional·Posted Jul 10, 2019·Updated Nov 8, 2023

In Brief

A clinical study evaluating Oral-agents/Enema for Colorectal Cancer. Completed, enrolled 40 participants across 1 site.

Detailed Summary

Mechanical bowel preparation for left-sided colorectal surgery remains standard in most cases. However, there are some discrepancies on how to prepare the bowl, while rectal enema and oral agents are both available methods. The knowledge of intestinal microbiome role on surgical outcomes is increasing, since few recent reports linked microbiome composition to postoperative complications, such as anastomotic insufficiency. Although, it is not clear how the bowel preparation affects the gut microbiome. Therefore, different bowel preparation techniques impact on gut microbiome will be studied.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesLithuania

Timeline

N/ACompletedFinished
2020202120222023202420252026
First PostedJul 10, 2019
Enrollment StartApr 8, 2021
Primary CompletionAug 1, 2022
Study CompletionNov 1, 2023
TodayJul 2, 2026
Enrollment to primary: 1.3 yearsPosted 7.0 years ago

Interventions

Oral-agents/Enemaother

1. Oral-agents for mechanical bowel preparation prior to left-side colorectal resection 2. Enema for mechanical bowel preparation prior to left-side colorectal resection