CI

At a glance

ClinicalIndex Comparison Record
Phase 1Completed· 200 enrolled
Drug / intervention
INTP5 +1 morecombination
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04015232
NCT04015232Phase 1Completed

An Assessor-blind, Balanced, Parallel, Randomized, Two-treatment, Comparative Immunogenicity Study of Multiple Doses of INTP5 of Intas Pharmaceuticals Limited, India Against Neulasta® of Amgen Inc., USA Administered Subcutaneously in Healthy, Adult, Human Subjects Under Fed Condition.

Intas Pharmaceuticals, Ltd.·interventional·Posted Jul 10, 2019·Updated Oct 4, 2019

In Brief

A Phase 1 clinical trial evaluating INTP5 and US Neulasta for Immunogenicity and Healthy Volunteers. Completed, enrolled 200 participants across 1 site.

Detailed Summary

The study was an assessor-blind, balanced, parallel, randomized, two-treatment, comparative immunogenicity study of multiple doses of subcutaneous (SC) Pegfilgrastim injection (6 mg/0.6 mL; Intas Pharmaceuticals Ltd. proposed biosimilar INTP5 compared to innovator product, US-Neulasta) in healthy, adult, human subjects under fed conditions.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesIndia

Timeline

Phase 1CompletedFinished
201820192020202120222023202420252026
First PostedJul 10, 2019
Enrollment StartFeb 26, 2018
Primary CompletionJun 5, 2018
TodayJul 2, 2026
Enrollment to primary: 3 monthsPosted 7.0 years ago

Interventions

INTP5combination

INTP5, a pegfilgrastim biosimilar to US Neulasta.

US Neulastacombination

US Neulasta: FDA approved pegfilgrastim innovator product.