CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 309 enrolled
Drug / intervention
Mindfulness Based Stress Reduction +1 morebehavioral
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04016415
NCT04016415N/ACompleted

Decreasing Stress in Diabetes: A Randomized Controlled Trial

Milton S. Hershey Medical Center·interventional·Posted Jul 11, 2019·Updated Oct 2, 2025

In Brief

A clinical study evaluating Mindfulness Based Stress Reduction and Stress Management Education for Stress and 2 related conditions. Completed, enrolled 309 participants across 1 site.

Detailed Summary

The purpose of this study is to conduct a randomized controlled trial (RCT) to determine the effects of an online 6-month Mindfulness-based stress reduction (MBSR) intervention compared to an active control Stress Management Education (SME) on glucose control in adults with uncontrolled type 1 or type 2 diabetes. The study will randomize at least 290 adults with uncontrolled diabetes to a 6-month MBSR intervention or SME control. Both MBSR and SME will be delivered online by experienced instructors in a live interactive virtual classroom using videoconferencing. Outcomes will be assessed at baseline, a follow-up phone call after Class #4, and study visits at 2-months (2MO) and 6-months (6MO).

Study Details

Timeline

N/ACompletedFinished
2020202120222023202420252026
First PostedJul 11, 2019
Enrollment StartJul 28, 2020
Primary CompletionAug 9, 2024
TodayJul 2, 2026
Enrollment to primary: 4.0 yearsPosted 7.0 years ago

Interventions

Mindfulness Based Stress Reductionbehavioral

Subjects randomized to Mindfulness-Based Stress Reduction (MBSR) will receive the 8-week University of Massachusetts Authorized MBSR curriculum followed by monthly mindfulness boosters in Months 3 to 6. The University of Massachusetts MBSR curriculum was selected for the intervention, as it is the most standardized and researched mindfulness program that has been shown to reduce psychological distress in various patient populations.

Stress Management Educationbehavioral

Subjects randomized to Stress Management Education (SME) will receive health education on nutrition (adapted for the type 2 diabetes population), exercise as gentle stretching to match yoga in MBSR, and other general health topics that may be relevant to the type 2 diabetes population such as sleep, time management, etc. Stress Management Education does not have any mindfulness in it. Stress Management Education was specifically created as a control condition for MBSR studies so it matches MBSR for time, social support, homework, etc.