At a glance
ClinicalIndex Comparison RecordStandardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Perioperative Multimodal General Anesthesia Focusing on Specific CNS Targets in Patients Undergoing Cardiac Surgeries
In Brief
A Early Phase 1 clinical trial evaluating Ropivacaine, Ketamine, and 6 other interventions for Coronary Artery Disease and Delirium. Completed, enrolled 22 participants across 1 site.
Detailed Summary
The main purpose of this study is to determine whether a rational strategy of EEG guided multimodal general anesthesia using target specific sedative and analgesics could result in enhanced recovery after anesthesia and surgery, decrease in postoperative delirium, and decrease in long term postoperative cognitive dysfunction up to 6 months following cardiac surgery.
Study Details
Timeline
Interventions
Intraoperative bilateral PIFB block with 20 mL of 0.25% Ropivicaine on either side of the sternum after anesthetic induction but before surgical incision
Intraoperative infusion
Intraoperative infusion
Intraoperative infusion
Intraoperative intermittent bolus
Intraoperative infusion
Intraoperative inhaled as needed
Post-operative infusion
Post-operative infusion
Perioperative monitoring