CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 327 enrolled
Drug / intervention
AXS-05 +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04019704
NCT04019704Phase 3Completed

AXS-05-MDD-301: A Randomized, Double-Blind, Placebo-Controlled Trial of AXS-05 in Subjects With Major Depressive Disorder

Axsome Therapeutics, Inc.·interventional·Posted Jul 15, 2019·Updated Oct 12, 2022

In Brief

A Phase 3 clinical trial evaluating AXS-05 and Placebo for Depression and Major Depressive Disorder. Completed, enrolled 327 participants across 43 sites.

Detailed Summary

A Phase 3, randomized, double-blind, placebo-controlled, multicenter trial of AXS-05 in patients with major depressive disorder (MDD).

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

Phase 3CompletedFinished
2020202120222023202420252026
First PostedJul 15, 2019
Enrollment StartJun 20, 2019
Primary CompletionNov 26, 2019
Study CompletionDec 5, 2019
TodayJul 2, 2026
Enrollment to primary: 5 monthsPosted 7.0 years ago

Interventions

AXS-05drug

Oral AXS-05 tablets, taken daily for 6 weeks.

Placebodrug

Placebo to match oral AXS-05 tablets, taken daily for 6 weeks.