CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 375 enrolled
Drug / intervention
Contingency Management for adherence +1 morebehavioral
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04024059
NCT04024059N/ACompleted

Contingency Management to Enhance Office-Based Buprenorphine Treatment

Johns Hopkins University·interventional·Posted Jul 18, 2019·Updated Mar 12, 2025

In Brief

A clinical study evaluating Contingency Management for adherence and Contingency Management for abstinence for Opioid-use Disorder. Completed, enrolled 375 participants across 1 site.

Detailed Summary

Contingency Management interventions provide incentives to substance abuse patients when patients meet therapeutic goals. This project will compare the effectiveness of two Contingency Management interventions (which the investigators have named "Buprenorphine Adherence and Opiate Abstinence" and "Buprenorphine Adherence Only") and Standard Medical Management for treating adults with opioid use disorder. Participants (N=375) will be randomly assigned to one of the three groups. Buprenorphine Adherence and Opiate Abstinence and Buprenorphine Adherence Only participants will receive incentives for daily buprenorphine use. Buprenorphine Adherence and Opiate Abstinence participants also will receive incentives for providing opiate-negative saliva samples. Daily buprenorphine use and opiate abstinence will both be remotely verified using smartphone-enabled video directly observed therapy (Video DOT). All participants will be receiving or referred to receive buprenorphine treatment and will complete assessments every 4 weeks during a 12-week intervention period.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States

Timeline

N/ACompletedFinished
2020202120222023202420252026
First PostedJul 18, 2019
Enrollment StartJan 31, 2020
Primary CompletionJun 30, 2023
Study CompletionJul 1, 2024
TodayJul 2, 2026
Enrollment to primary: 3.4 yearsPosted 7.0 years ago

Interventions

Contingency Management for adherencebehavioral

Incentives contingent on buprenorphine adherence

Contingency Management for abstinencebehavioral

Incentives contingent on opiate abstinence