CI

At a glance

ClinicalIndex Comparison Record
N/ARecruiting· 4,052 target
Drug / intervention
Hypofractionated Radiotherapy +1 moreradiation
Likely dose
Not stated in record
Key inclusion· 14
  • ✓Female
  • ✓Age 18-70 years
  • ✓Single lesion or multiple lesions removable by single quadrantectomy
  • ✓Breast conserving surgery with negative margins
Key exclusion· 14
  • ✕T4 or M1 breast cancer
  • ✕Supraclavicular or internal mammary nodes metastases
  • ✕DCIS only without invasive component
  • ✕Bilateral breast cancer or contralateral invasive breast cancer history

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04025164
NCT04025164N/ARecruitingUpdate OverdueUpdated 83mo ago · Completion was 36mo ago
Enrollment Stalled
Long Recruiting
Update Overdue
CompareCT.gov

Hypofractionated Versus Conventional Fractionated Radiotherapy After Breast Conserving Surgery：a Multi-center Phase III Randomized Clinical Trial

Fudan University·interventional·Posted Jul 18, 2019·Updated Jul 18, 2019

In Brief

A clinical study evaluating Hypofractionated Radiotherapy and Conventional fractionated Radiotherapy for Breast Cancer. Currently recruiting, targeting 4,052 participants across 5 sites.

Signals

Enrollment appears stalled

Detailed Summary

The study was designed to investigate whether hypofractionated radiotherapy(HF-RT) is noninferior to conventionally fractionated radiotherapy (CF-RT) in terms of tumor loco-regional control for patients after breast conserving surgery

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsBreast Cancer
CountriesChina
Collaborators--

Timeline

N/ARecruiting
2019202020212022202320242025202620272028
First PostedJul 18, 2019
Enrollment StartJul 1, 2018
Primary CompletionJun 30, 2023
Study CompletionJun 30, 2028
TodayJul 2, 2026
Enrollment to primary: 5.0 yearsPosted 7.0 years ago

Interventions

Hypofractionated Radiotherapyradiation

daily fractions, 2.66 Gy/3.2 Gy per fraction to whole breast/tumor bed, five fractions per week

Conventional fractionated Radiotherapyradiation

daily fractions, 2 Gy per fraction, five fractions per week