CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 80 enrolled
Drug / intervention
Oral B Indicator 123 +3 moreother
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04025684
NCT04025684N/ACompleted

Randomized Controlled Examiner-Blind Methodology Development Study To Investigate The Plaque Removal Efficacy Of Manual Toothbrushes In Healthy Dentate Subjects

GlaxoSmithKline·interventional·Posted Jul 19, 2019·Updated Jan 28, 2021

In Brief

A clinical study evaluating Oral B Indicator 123, Dr Best Original, and 2 other interventions for Dental Plaque and Oral Hygiene. Completed, enrolled 80 participants across 1 site.

Detailed Summary

This clinical methodology development study will evaluate the plaque removal efficacy of four marketed manual toothbrushes, with differing bristle types and brush head designs, in healthy dentate participants. Changes in supra-gingival plaque accumulation will be assessed after first use and following 1-and 4-weeks treatment (twice-daily brushing), using two different clinical measures of dental plaque. Study participants will abstain from oral hygiene for a period of 12-18 hours prior to each assessment visit. Data generated will inform the design of future clinical studies investigating the plaque removal efficacy of manual toothbrushes.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited Kingdom
Collaborators--

Timeline

N/ACompletedFinished
2020202120222023202420252026
First PostedJul 19, 2019
Enrollment StartSep 30, 2019
Primary CompletionDec 10, 2019
TodayJul 2, 2026
Enrollment to primary: 2 monthsPosted 7.0 years ago

Interventions

Oral B Indicator 123other

Manual toothbrush (medium bristle stiffness; compact head, UK market).

Dr Best Originalother

Manual toothbrush (medium bristle stiffness; regular head, German market)

Dr Best Multi Expertother

Manual toothbrush (medium bristle stiffness; compact head, German market)

parodontax Interdentalother

Manual toothbrush (soft bristle stiffness; compact head, German market)