CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 121 enrolled
Drug / intervention
Respiratory exchange ratio +6 moredevice
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04029532
NCT04029532N/ACompleted

Factors Associated With Obesity in Adult Women: Respiratory Exchange Ratio, Heart Rate Variation and Body Image

National Taiwan University Hospital·observational·Posted Jul 23, 2019·Updated Aug 12, 2020

In Brief

An observational study evaluating Respiratory exchange ratio, Heart rate variability, and 5 other interventions for Obesity. Completed, enrolled 121 participants across 1 site.

Detailed Summary

The prevalence of obesity all over the world has increased year by year, and how to effectively prevent and treat obesity has become an important health care issue. Many adjustable and nonadjustable causes of obesity have been proposed, such as unbalanced eating habits, lack of physical activity, psychological factors, and genes. The practice guidelines recommended lifestyle modification interventions which include diet control combined with regular exercise as the core treatment for obesity, but the effects on different ethnic groups are not ideal. In order to provide more choices for future weight loss intervention, it would be important to find out more risk factors for obesity. Previous studies have shown that lower sympathetic activity assessed by heart rate variability was related to obesity; obese men have higher respiratory exchange rates which might indicate they are more likely to use carbohydrates as a source of energy, and therefore, fat cannot be effectively consumed and led to an accumulation in the body. Furthermore, previous studies showed that Asians are less satisfied with their body image than other races, and women are more dissatisfied than men. Poor body image will lead to a series of effects, such as changes in eating habits, hormonal changes, depression, etc., eventually forming a vicious circle of obesity. However, most aforementioned Asians in these studies are immigrants living in overseas areas such as the Americas, and cannot fully represent the ethnic groups in Asia. Therefore, the purpose of this study are (1) to investigate the physiological and psychological factors influence obesity in adult women, including respiratory exchange rate, heart rate variability, and body image, and (2) to examine the correlations among these risk factors and different degree of obesity.

Study Details

Study Typeobservational
Allocation--
Masking--
Primary Purpose--
ConditionsObesity
CountriesTaiwan
Collaborators--

Timeline

N/ACompletedFinished
2020202120222023202420252026
First PostedJul 23, 2019
Enrollment StartApr 1, 2019
Primary CompletionOct 26, 2019
Study CompletionJan 14, 2020
TodayJul 2, 2026
Enrollment to primary: 7 monthsPosted 6.9 years ago

Interventions

Respiratory exchange ratiodevice

Ask participants to supine on bed, using a ventilator hood cover upon their head. Measure respiratory exchange ratio for 15 minutes.

Heart rate variabilitydevice

Ask participants to supine on bed for 10 minutes, connect electrodes on their right wrist. Measure heart rate variability for 5 minutes.

Body compositiondevice

Ask participants to supine on bed for 10 minutes, connect electrodes on their right wrist and right foot. Measure body composition.

Eating behaviorbehavioral

Fill in questionnaire (Three-Factor Eating Questionnaire, revised 18-item, TFEQ-18).

Physical activity recallbehavioral

Fill in questionnaire (Seven-days Physical Activity Recall, 7-d PAR).

Depressionbehavioral

Fill in questionnaire (Mongomery-Asberg Depression Rating Scale, MADRS).

Body imagebehavioral

Fill in questionnaire (multi-directional self-body relationship questionnaire (MBSRQ), figure rating scale (FRS)).