CI

At a glance

ClinicalIndex Comparison Record
N/AActive· 600 target
Drug / intervention
Meditationbehavioral
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04031716
NCT04031716N/AActiveUpdate OverdueUpdated 12mo ago · Completion was 6mo ago
Enrollment Stalled

Genetic, Epigenetic, Psychosocial, and Biological Determinants of Post-surgical Pain After Pectus or Spine Surgery

Children's Hospital Medical Center, Cincinnati·interventional·Posted Jul 24, 2019·Updated Jun 13, 2025

In Brief

A clinical study evaluating Meditation for Pain, Postoperative and 2 related conditions. Active but no longer recruiting, targeting 600 participants across 1 site.

Signals

Enrollment appears stalled

Detailed Summary

This will be a prospective study to determine the association between specific genotypes, epigenetics, behavioral, social and biological factors, with the phenotypes, defined by pain perception, postoperative pain, analgesic effects, side effects to perioperative analgesics, chronic postoperative pain, and gene expression in patients following pectus excavatum repair.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

N/AActiveOverdue
20192020202120222023202420252026
First PostedJul 24, 2019
Enrollment StartJul 6, 2018
Primary CompletionDec 31, 2025
TodayJul 2, 2026
Enrollment to primary: 7.5 yearsPosted 6.9 years ago

Interventions

Meditationbehavioral

Participants assigned to the Meditation intervention will receive focused attention meditation training preoperatively, and encouraged to meditate for 20 minutes per day before surgery. In the postoperative inpatient period, the participants will be offered standard holistic health care, reinforcement of meditation training, and encouragement to practice at least 20 minutes of guided focused-attention meditation with breath as their focus, utilizing the MUSETM headband for bio-feedback, every day during their hospital stay. They will be asked to continue using the MUSETM neurofeedback-assisted meditation after hospital discharge, until their visit to repeat pain testing, at which time they will return the MUSETM headband.