CI

At a glance

ClinicalIndex Comparison Record
Phase 2Unknown· 14 enrolled
Drug / intervention
Recombinant EphB4-HSA Fusion Proteinbiological
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04033432
NCT04033432Phase 2Unknown

A Phase II Study of sEphB4-HSA in Metastatic Castration-Resistant Prostate Cancer

Northwestern University·interventional·Posted Jul 26, 2019·Updated Apr 27, 2022

In Brief

A Phase 2 clinical trial evaluating Recombinant EphB4-HSA Fusion Protein for Castration Levels of Testosterone and 9 related conditions. Targeting 14 participants across 3 sites.

Detailed Summary

The purpose of this phase II, single-arm, open-label, three center study is to evaluate the efficacy, safety, and tolerability of sEphB4-HSA in patients with mCRPC (metastatic castration-resistant prostate cancer). The study drug, sEphB4-HAS, is a form of protein that has not been approved for sale by the United States Food and Drug Administration (FDA). The study drug prevents tumor cells from multiplying and blocks several compounds that promote the growth of blood vessels that bring nutrients to the tumor.

Study Details

Timeline

Phase 2UnknownOverdue
2020202120222023202420252026
First PostedJul 26, 2019
Enrollment StartSep 20, 2019
Primary CompletionFeb 5, 2021
Study CompletionJun 30, 2022
TodayJul 2, 2026
Enrollment to primary: 1.4 yearsPosted 6.9 years ago

Interventions

Recombinant EphB4-HSA Fusion Proteinbiological

Given IV