At a glance
ClinicalIndex Comparison RecordPhase 3Completed· 38 enrolled
Drug / intervention
Melatonin 10 MG Oral Tablet +2 moredrug
Likely dose
Melatonin 10 MG Oral Tabletfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
The Effect of Melatonin Administration on Sedation Level as Adjuvant to Propofol in Mechanically Ventilated Traumatic Brain Injury Patient: RCT
In Brief
A Phase 3 clinical trial evaluating Melatonin 10 MG Oral Tablet, Propofol, and 1 other intervention for TBI (Traumatic Brain Injury). Completed, enrolled 38 participants across 1 site.
Detailed Summary
This study assess the effect of administration of exogenous melatonin as adjuvant to propofol on the level of sedation and consequently the rate of propofol infusion.
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsTBI (Traumatic Brain Injury)
CountriesEgypt
Collaborators--
Timeline
Phase 3CompletedFinished
201820192020202120222023202420252026
Enrollment StartJan 2018
Primary CompletionApr 2018
Study CompletionApr 2018
First PostedJul 2019
TodayJul 2026
First PostedJul 26, 2019
Enrollment StartJan 1, 2018
Primary CompletionApr 1, 2018
Study CompletionApr 5, 2018
TodayJul 2, 2026
Enrollment to primary: 3 monthsPosted 6.9 years ago
Interventions
Melatonin 10 MG Oral Tabletdrug
Melatonin tablets
Propofoldrug
propofol amp
Placebo oral tabletdrug
sugar pill manufactured to mimic melatonin tablets