CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 238 enrolled
Drug / intervention
Wetting method (WTM) +1 morebehavioral
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04036708
NCT04036708N/ACompleted

Caregiver Early Child Development Training for Preventing Konzo From Toxic Cassava in the Democratic Republic of Congo (DRC)

Michigan State University·interventional·Posted Jul 30, 2019·Updated Apr 24, 2024

In Brief

A clinical study evaluating Wetting method (WTM) and Mediational Intervention for Sensitizing Caregivers (MISC) for Malnutrition and Manihot Species Poisoning. Completed, enrolled 238 participants across 1 site.

Detailed Summary

The proposed research adapted the caregiver training and child neurodevelopmental assessment capacity that the PI previously built in Uganda beginning in 2008, to a community-based intervention model for the prevention of konzo in the Democratic Republic of Congo.

Study Details

Timeline

N/ACompletedFinished
2020202120222023202420252026
First PostedJul 30, 2019
Enrollment StartApr 1, 2021
Primary CompletionAug 31, 2022
TodayJul 2, 2026
Enrollment to primary: 1.4 yearsPosted 6.9 years ago

Interventions

Wetting method (WTM)behavioral

The wetting method is an evidence-based, simple process to remove cyanogens from cassava flour. It involves teaching women to add water to cassava flour and allow it to stand for 2 h in the sun or 5 h in the shade for the hydrogen cyanide gas to escape. Colorfully illustrated and durable laminated posters depicting the WTM were distributed to participating households. Women received this training bi-weekly for 12 months.

Mediational Intervention for Sensitizing Caregivers (MISC)behavioral

The study team used MISC to train DRC mothers in practical day-to-day activities with their children to enhance 5 key mediational processes: 1) focusing (getting the child's attention and engaging directing them to learning experiences); 2) exciting (communicating excitement, appreciation, and affection with the learning experience); 3) expanding (making the child aware of how the learning experience transcends the present situation and can include past and future issues beyond the immediate need of the moment); 4) encouraging (emotional support to foster the child's sense of security and competence); and 5) regulating (helping to direct the child's behavior in constructive ways with a goal towards self-regulation).