CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 71 enrolled
Drug / intervention
LYR-210 +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04041609
NCT04041609Phase 2Completed

A Phase II, Randomized, Blinded, Sham Procedure-Controlled, Parallel-Group Trial to Evaluate the Efficacy, Safety and Tolerability of LYR-210 in Adult Subjects With Chronic Sinusitis (LANTERN Study)

Lyra Therapeutics·interventional·Posted Aug 1, 2019·Updated Jul 25, 2023

In Brief

A Phase 2 clinical trial evaluating LYR-210 and Sham comparator for Chronic Sinusitis and Chronic Rhinosinusitis (Diagnosis). Completed, enrolled 71 participants across 22 sites in 5 countries.

Detailed Summary

This is a Phase II, Randomized, Blinded, Sham Procedure-Controlled, Parallel-Group Trial to Evaluate the Efficacy, Safety and Tolerability of LYR-210 in Adult Subjects with Chronic Sinusitis.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesAustralia, Austria, Czechia, New Zealand, Poland
Collaborators--

Timeline

Phase 2CompletedFinished
2020202120222023202420252026
First PostedAug 1, 2019
Enrollment StartMay 9, 2019
Primary CompletionMar 25, 2020
Study CompletionFeb 4, 2021
TodayJul 2, 2026
Enrollment to primary: 11 monthsPosted 6.9 years ago

Interventions

LYR-210drug

A single administration of LYR-210 depot

Sham comparatorother

Sham comparator