At a glance
ClinicalIndex Comparison RecordStandardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Intraosseous Vancomycin in Primary Total Hip Arthroplasty - Designing a Protocol
In Brief
A Phase 4 clinical trial evaluating Experimental Intraosseous vancomycin 500mg in 250 mL NS and Standard IV administration of vancomycin for Prosthetic Joint Infection and 2 related conditions. Completed, enrolled 23 participants across 1 site.
Detailed Summary
The objective of this study is to evaluate a novel vancomycin intraosseous administration protocol vs a standard IV vancomycin administration protocol for primary total hip arthroplasty patients.
Study Details
Timeline
Interventions
500mg of Vancomycin in 250 mL of normal saline will be injected into a pre-specified region of the greater trochanter during primary total hip arthroplasty.
IV antibiotics (cefepime \& vancomycin) are started in pre-op approximately 1 hour prior to incision (vancomycin dose weight-based at approximately 15mg/kg, generally 1000-1750mg in 500 mL NS).