CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 18 enrolled
Drug / intervention
Unified Protocol adapted for smoking cessationbehavioral
Likely dose
Not stated in record
Key inclusion· 6
  • Diagnosed with COPD (documented in electronic health record)
  • Current daily smokers: 5+ cigarettes per day over past 30 days
  • Intent to quit smoking within next 60 days
  • At least moderate smoking for affective regulation (SMQ-R coping subscale ≥30)
Key exclusion· 1
  • Medical or psychiatric conditions precluding informed consent or study procedures (e.g., moderate-to-severe dementia, severe uncontrolled schizophrenia)

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04043728
NCT04043728N/ACompleted

Addressing Psychological Risk Factors Underlying Smoking Persistence in COPD Patients: The Fresh Start Study

Rush University Medical Center·interventional·Posted Aug 2, 2019·Updated Mar 17, 2021

In Brief

A clinical study evaluating Unified Protocol adapted for smoking cessation for Copd and 4 related conditions. Completed, enrolled 18 participants across 1 site.

Detailed Summary

Chronic Obstructive Pulmonary Disease (COPD) is caused primarily by smoking and smoking cessation is the first-line treatment for slowing disease progression. Despite this, nearly 50% of COPD patients continue to smoke following diagnosis. Smokers with COPD report high rates of co-occurring conditions - nicotine dependence, depression, and anxiety - which serve as barriers to quitting. The current study will pilot test a behavioral intervention designed to target the common psychological factors underlying these co-occurring conditions and foster smoking cessation among COPD patients.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
2020202120222023202420252026
First PostedAug 2, 2019
Enrollment StartSep 9, 2019
Primary CompletionMar 31, 2020
TodayJul 2, 2026
Enrollment to primary: 7 monthsPosted 6.9 years ago

Interventions

Unified Protocol adapted for smoking cessationbehavioral

Treatment components are cognitive-behavioral strategies adapted from the Unified Protocol (UP) for the Transdiagnostic Treatment of Emotional Disorders. Behavioral counseling strategies for smoking cessation, drawn from current US Public Health Service guidelines, are incorporated in each treatment module. All participants will be provided with the American Lung Association Freedom from Smoking guide to aid in their quit attempt.