CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 70 enrolled
Drug / intervention
ascorbic acid, +1 moredietary
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04046861
NCT04046861N/ACompleted

"Influence of High Vitamin C Dose on Lactate During Extracorporeal Circulation for Heart Surgery and During the 24 Hours Thereafter." (double Blind Prospective Randomised Study)

University Medical Centre Maribor·interventional·Posted Aug 6, 2019·Updated Feb 21, 2025

In Brief

A clinical study evaluating ascorbic acid, and Placebo (saline) for Hyperlactatemia and 4 related conditions. Completed, enrolled 70 participants across 1 site.

Detailed Summary

The aim of our study is to find out whether high doses of vitamin C before cardiopulmonary bypass and during the first 24 hours after that have and impact of lowering the incidence of hyperlactatemia.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesSlovenia
Collaborators--

Timeline

N/ACompletedFinished
2020202120222023202420252026
First PostedAug 6, 2019
Enrollment StartMar 1, 2023
Primary CompletionDec 1, 2023
Study CompletionSep 1, 2024
TodayJul 2, 2026
Enrollment to primary: 9 monthsPosted 6.9 years ago

Interventions

ascorbic acid,dietary

The vitamin C group will get high dose of intravenous vitamin C (ascorbic acid) before starting cardiopulmonary bypass, before removing aortic clamp and every 8 hours thereafter for additionaly 24 hours

Placebo (saline)other

The placebo group will get saline before starting cardiopulmonary bypass, before removing aortic clamp and every 8 hours thereafter for additionaly 24 hours