CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 534 enrolled
Drug / intervention
Dexpramipexole +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04046939
NCT04046939Phase 2Completed

A Randomized, Double-Blind, Placebo-Controlled Dose-Ranging Biomarker Study of the Effects of Dexpramipexole on Eosinophils in Subjects With Eosinophilic Asthma

Knopp Biosciences·interventional·Posted Aug 6, 2019·Updated Apr 13, 2023

In Brief

A Phase 2 clinical trial evaluating Dexpramipexole and Placebo for Eosinophilic Asthma and Asthma. Completed, enrolled 534 participants across 36 sites.

Detailed Summary

This is a randomized, double-blind, placebo-controlled, parallel-group, dose-ranging, multi-center study to evaluate the clinical effects of oral administration of dexpramipexole for 12 weeks on peripheral blood eosinophil count in subjects with eosinophilic asthma.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

Phase 2CompletedFinished
2020202120222023202420252026
First PostedAug 6, 2019
Enrollment StartAug 15, 2019
Primary CompletionDec 3, 2020
Study CompletionMar 2, 2021
TodayJul 2, 2026
Enrollment to primary: 1.3 yearsPosted 6.9 years ago

Interventions

Dexpramipexoledrug

dexpramipexole twice daily oral dosing for up to 12 weeks

Placebodrug

placebo twice daily oral dosing for up to 12 weeks