CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 397 enrolled
Drug / intervention
Brolucizumab 6mg +1 moredrug
Likely dose
Brolucizumab 6mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04047472
NCT04047472Phase 3Completed

A Twelve-Month, Randomized, Double-Masked, Multicenter, Phase III, Two-Arm Study Comparing the Efficacy and Safety of Brolucizumab 6 mg Versus Aflibercept in Chinese Patients With Neovascular Age-Related Macular Degeneration

Novartis Pharmaceuticals·interventional·Posted Aug 6, 2019·Updated Dec 9, 2024

In Brief

A Phase 3 clinical trial evaluating Brolucizumab 6mg and Aflibercept 2 mg for Neovascular Age-Related Macular Degeneration. Completed, enrolled 397 participants across 30 sites.

Detailed Summary

To compare brolucizumab to aflibercept in Chinese patients with untreated active choroidal neovascularization (CNV) secondary to age-related macular degeneration (AMD)

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesChina
Collaborators--

Timeline

Phase 3CompletedFinished
2020202120222023202420252026
First PostedAug 6, 2019
Enrollment StartNov 29, 2019
Primary CompletionFeb 28, 2024
TodayJul 2, 2026
Enrollment to primary: 4.2 yearsPosted 6.9 years ago

Interventions

Brolucizumab 6mgdrug

Intravitreal injection

Aflibercept 2 mgdrug

Intravitreal injection