CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 141 enrolled
Drug / intervention
whey protein isolate +3 moredietary
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT04048616
NCT04048616N/ACompleted

Impact of Protein and Alkali Supplementation on Skeletal Muscle in Older Adults

Tufts University·interventional·Posted Aug 7, 2019·Updated May 18, 2025

In Brief

A clinical study evaluating whey protein isolate, potassium bicarbonate (KHCO3), and 2 other interventions for Age-Related Sarcopenia and Muscle Loss. Completed, enrolled 141 participants across 1 site.

Detailed Summary

The central hypothesis is that higher protein intake and a neutralizing alkaline salt supplement will improve muscle performance and mass, compared to their respective placebos, in older men and postmenopausal women.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States

Timeline

N/ACompletedFinished
2020202120222023202420252026
First PostedAug 7, 2019
Enrollment StartJul 1, 2021
Primary CompletionDec 21, 2023
TodayJul 2, 2026
Enrollment to primary: 2.5 yearsPosted 6.9 years ago

Interventions

whey protein isolatedietary

one 15-25 gm (based on body weight) protein packet three times a day with each meal

potassium bicarbonate (KHCO3)dietary

two 13.5 mmol capsules three times a day with each meal

microcrystalline celluloseother

identical placebo capsule

maltodextrin powderother

isocaloric placebo powder